The p-value is a mathematical method for analyzing data. Unfortunately, it is often both misunderstood, misused, and miscommunicated in medical research. It’s emerging use is challenged by American Statistical Association (ASA) followed by a paper and an editorial in Journal of American Medical Association (JAMA). And this is good news. (more…)
We are proud that the idea behind Zignifica was selected for presentation at the EvidenceLive 2016 conference at Oxford University, UK in June 2016. (more…)
Clinical research is crucial for healthcare to improve. Clinical research concerns us all. Clinical research costs a lot of money. Clinical research is most often useless – but not always. It is Time to improve. (more…)
The aim of clinical research is to advance healthcare by new knowledge. This knowledge must, of course, be relevant for those it concerns, which is primarily patients and their providers. Unfortunately most clinical research is useless, mainly due to poor method/design and not focusing on clinical relevance. The ability to reproduce findings is a cornerstone…
The findings from clinical research can be difficult to translate into everyday care. The Number Needed to Treat (NNT) provides an easy to understand alternative for evaluating the relevance of findings. Here is a very easy way to find NNT from a study (more…)
Getting yellow fingernails from holding many cigarettes is not uncommon. However, I guess that few people would intuitively buy the argument that yellow nails can cause lung cancer. But if asked if cell phones can cause cancer, then it is not all that intuitively clear. Or how about coffee. A Google search of “coffee…
Stories are an important part of human traditions, and one of the most powerful ways to deliver a message – especially if we ca relate to the story. But no matter how compelling and convincing a story related to health and healthcare may be, it can never be a scientific proof. The story does, however,…
It ‘s hard to find relevant information among contradictory and sometimes misleading information in the medical news. As a consequence, valuable information may be lost, and useless information is taken seriously. (more…)
John Oliver discusses how and why media outlets so often report untrue or incomplete information as science. Entertaining and funny show, and yet still serious. (more…)
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